Prevalence of ESBL phenotype in uropathogens associated urinary tract infections in Bhopal, Madhya Pradesh, India

Abstract

The uropathogenic microbial strains and associated infectious diseases such as urinary tract infections remain a major infectious diseases threat worldwide. More likely females are much prone to getting UTIs and subsequent pathological consequences due to anatomical specifications. UTIs are ubiquitous with in India with a higher proportion in southern and central India. The emergence of MDR is major health concern associated with infectious diseases. Considering UTIs, and associated pathogens, ESBL producing uropathogenic microbial strains that least studied and reported in central part of India. In this study, we aimed Bhopal city, Madhya Pradesh, India for ESBL phenotype in uropathogenic microbial strains isolated from UTIs patients. In our findings, there is the prevalence of E. coli in all uropathogenic microbial strains among the 500 samples studied. Out of these, more than half (60%) were reported resistance for all major antibiotics. Here, from our study, E. coli was reported as a major MDR and ESBL (2% of MDR) producing uropathogenic microbial strains associated with onset and progression of infection in Bhopal city.